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TOPGUN

Shape-shifting molecule aids memory in fruit flies

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 TOPGUN    125

A protein that can switch shapes and accumulate inside brain cells helps fruit flies form and retrieve memories, a new study finds.

Such shape-shifting is the hallmark move of prions — proteins that can alternate between two forms and aggregate under certain conditions. In fruit flies’ brain cells, clumps of the prionlike protein called Orb2 stores long-lasting memories, report scientists from the Stowers Institute for Medical Research in Kansas City, Mo. Figuring out how the brain forms and calls up memories may ultimately help scientists devise ways to restore that process in people with diseases such as Alzheimer’s.

The new finding, described online November 3 in Current Biology, is “absolutely superb,” says neuroscientist Eric Kandel of Columbia University. “It fills in a lot of missing pieces.”

People possess a version of the Orb2 protein called CPEB, a commonality that suggests memory might work in a similar way in people, Kandel says. It’s not yet known whether people rely on the prion to store long-term memories. “We can’t be sure, but it’s very suggestive,” Kandel says.

When neuroscientist Kausik Si and colleagues used a genetic trick to inactivate Orb2 protein, male flies were worse at remembering rejection. These lovesick males continued to woo a nonreceptive female long past when they should have learned that courtship was futile. In different tests, these flies also had trouble remembering that a certain odor was tied to food.

https://www.sciencenews.org/article/shape-shifting-molecule-aids-memory-fruit-flies?tgt=nr

Shape-shifting?????????? :lulz1:

 

 

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 radio doc    373

who made the horsefly stupid enough to land on hillarys nose? will they attempt to land a fruitfly? will its little feet be covered in political correctness?

seriously, i dont think its right to make flies turn liberal!

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 Jostler    2,216
26 minutes ago, radio doc said:

who made the horsefly stupid enough to land on hillarys nose? will they attempt to land a fruitfly? will its little feet be covered in political correctness?

seriously, i dont think its right to make flies turn liberal!

oh you have no clue how  deep this deception goes my friend.  Did you know that in Australia they make fruit flies go LIBERAL (which is RIGHT) and send all the horseflies to LABOR which is left.  Which explains a lot about Gillard...horseface..horsefly....its all there ya just gotta connect the dots :)

Foreigners who happen to be right wingers can easily find themselves labeled lefties, stuffed under a table and left for dead in some non-descript bar in Sydney. 

If you can remember to drink LIBERALLY when in Oz you should be ok.

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