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Fourth echelon

Testing antibiotics against bacteria faster with new chip

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TORONTO, May 26 (UPI) -- A new chip could make it easier for doctors to prescribe the correct antibiotic, if one is even needed at all, by quickly analyzing the effectiveness of the antibiotic on bacteria collected from patient samples.

Patient samples are flowed through the chip and samples collect at the bottom of well-like structures where bacteria mix with the antibiotic to be tested and a signal molecule called resazurin. If the antibiotic is not successful, the bacteria will metabolize resazurin into resorufin, changing the electrochemical signature of the sample. If nothing happens, the antibiotic will have successfully killed the bacteria.




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